| Group | Club/Team Name | Team ID | Head Coach |
| D21 | Bilu International Soccer Academy BISA Wolves 16B |
03045-001AB8U-2016 | Ademir Cabral |
| D22 | Cainhoy Athletic Soccer Club CASC 16 Pumas |
03006-001AB8U-2391 | Patrick Coyle |
| D23 | James Island Youth SC FC Charleston 2016/17 Boys Navy |
03001-001AB8U-1200 | Sachin Patel |
| D24 | James Island Youth SC JIYSC 2016 Boys Red Dylan |
03001-001AB8U-0026 | Dylan Guice |
| D25 | James Island Youth SC JIYSC 2016 Boys Red Guice |
03001-001AB8U-0025 | Dylan Guice |
| D26 | Kickoff Soccer Academy - 01 KOSA 2016 Boys Nosa |
03033-001AB8U-0015 | Robert Nosakhare |
| D27 | South Carolina Surf Soccer Club SC Surf MP 16 Black |
03008-001AB8U-5648 | Carlos Ortiz |