| Group | Club/Team Name | Team ID | Head Coach |
| D21 | Bluffton Rush Soccer Club - 01 Bluffton Rush 2012 Boys |
03040-001AB2U-0004 | Richard Reynolds |
| D22 | Charleston Soccer Club LLC CSC 12 Boys Navy South |
03034-001AB2U-0061 | Daniel Cohen |
| D23 | Charleston Soccer Club LLC CSC 12 Boys Yellow North |
03034-001AB2U-0060 | Dylan Such |
| D24 | Daniel Island SA DISA U12 Arsenal Jr Academy |
03030-001AB2U-0015 | Haddad Khouri |
| D25 | James Island Youth SC FC Charleston 2012 Boys Navy |
03001-001AB2U-1196 | William Majewski |
| D26 | Kingston United Soccer Club Kingston 12 Boys |
03044-001JB2U-0004 | Justin Schools |
| D27 | Mt. Pleasant SC - 01 MPRD Red Wolves |
03007-001RB2U-0012 | Robert Gamard |
| D28 | South Carolina Surf Soccer Club SC Surf 12 Pre GA |
03008-001PG3U-5649 | Stephen Sweeney |
| D29 | Beach United FC - 01 Beach United FC - Wolves |
03022-001AB2U-1269 | Victor Ruiz |
| D210 | Charleston City FC CCFC U12 Boys White |
03014-001JB2U-0036 | Johnathan Moore |